Pathology with Dr. John Minarcik: Lupus

Notes on Lupus Erythematosus:

■ In Lupus, the body fails to recognize its own self, and attacks it.
■ A typical case may be a young woman presenting with renal failure.
■ You might see a symmetrical “Butterfly rash”.

■ Haematological manifestation of expression of Lupus seen in 100% of patients.
■ Kidney failure most feared early manifestation of disease, but only present in about half of patients.

■ Arthritis is much more common as well as skin lesions, fever, fatigue, and weight loss.
■ “Where you have nuclei is where Lupus attacks!”
■ 50% or more of clinical presentations are ArthriticHematologicRenal

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